The Battle Against Hospital Yeast Infection
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On the rise today is the number of patients in hospital who are developing fungal or yeast infections that have a high mortality rate. A report in the journal Critical Care looks at two ways to cut down mortality and morbidity related to yeast, a single drug anti-fungal prophylaxis (SAP) and a multi-drug regimen of selective digestive tract decontamination (SDD).
Data from over 5000 patients was correlated by a team from the Netherlands who wanted to compare anti-fungal preventative therapies and how effective they were. SAP and SDD treatments in the critically ill were looked at and both were found to reduce the number of yeast infections. In terms of cutting back yeast colonization and infection SDD was found to be more effective than SAP apart from on candidemia. This did better with SAP treatment. Overall both reduced yeast mortality rates.
The authors write,
“Systemic drugs may be advised as prophylaxis in patients with a high risk of developing Candida bloodstream infections, whereas SDD may be given to critically ill patients to prevent Candida colonization and infection.”
It is hard to tell the difference between normal yeast colonies and infection, and with blood tests taken to diagnose being just 70% accurate, this makes managing yeast infections in hospital effectively a hard task. Something needs to be done though as in 1995 yeast was the fourth most common hospital acquired infection in Europe and in the USA. There is a lack of more recent data so it could be even more common now.
http://www.sciencedaily.com/releases/2007/12/071205190906.htm
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